People

Prof. Dr. Hubert Bahl Head, Division of Microbiology, Institute of Biological Sciences University of Rostock Albert-Einstein-Str. 3 D-18051 Rostock

I am a Professor in Medical Systems Biology and the University Medical Centre Groningen. The research in my lab is focused on complex regulation of mammalian lipid and carbohydrate metabolism, eventually aiming at network-based therapies. We combine dynamic computer simulations with quantitative metabolomics, 13C fluxomics, proteomics and transcriptome analysis, and in depth biochemical analysis. This allows to predict and understand ‘emergent’ properties, those properties that are counterintuitive ...

We are very interested in applying a systems approach (i.e. model-based concepts and related computational tools) to problems from the biological domain. In particular, we are doing research in computational systems biology, targetting the following topics:

• Parameter estimation (inverse problems, model calibration) in biochemical pathways
• Optimal experimental design (optimal dynamic experiments) for Systems Biology
• Dynamic optimization (optimal control) of biosystems and bioprocesses

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Martijn Bekker (1979) was born in Amstelveen (The Netherlands). He started his studies in biology in 1997 at the University of Amsterdam, and graduated in 2003 with specializations in molecular microbiology and in immunology. The internships during his undergraduate studies were carried out in the labs of Prof. dr. B. Oudega (VU, Amsterdam, The Netherlands) and Prof. dr. F. Heffron (OHSU, Portland, Oregon, USA). He continued with his graduate studies in 2003 in the Laboratory for Molecular Microbial ...

With a background in the statistical mechanics of disordered systems, my research focusses on the interface between statistical physics and molecular biology. At the centre is the relationship between fluctuations and noise in biological systems, the corresponding statistical ensembles, and biological function. This connection emerges at very different levels and timescales, from stochastic modeling of gene expression to the population dynamics of regulatory DNA.

I am interested in the coupling of global regulation and metabolism in E. coli. To analyze this I construct and analyze defined mutant strains. These strains are characterized in bioreactor experiments of different types (batch, conti, pulse ...) and measurements on the level of metabolites, mRNA, and protein are applied. For all projects there are cooperation partners that use the data in modeling approaches either from the MPI Magdeburg or from the SUMO consortium.

I am a phd student working on statistical physics and complex systems and applying concepts from these fields to biology.

My research interests are in the physiology of bacteria subjected to stress. The focus of my recent research has been the structure and function of regulated transport systems and ion channels involved in cellular homeostasis. These transporters and channels respond to specific signals by a change in activity that either corrects the imposed stress or protects the cell during exposure to the stress. Our systems biology interests are in the interplay of different enzymes systems and transporters ...

Senior Research Scientist at SINTEF, Dept. of Biotechnology and Nanomedicine, Research Group Mass Spectrometry

I am a PhD student working the group of Zoya Ignatova. Cellular and extracellular changes like crowding and osmotic stress conditions play a major role in protein aggregation. A change in the cytoplasmic composition is the result of an interplay between high osmotic pressures outside the cell volume and the cellular response to it in terms of uptake of K+ and secondary organic osmolytes. My research focuses on elucidating the role of natural osmolytes (known also as chemical chaperones or compatible ...

Phd student University of Ulm Institute of Microbiology and Biotechnology Albert-Einstein- Allee 11 89069 Ulm, Germany

I am currently Professor of Systems Biology at the University of Manchester. My research interests focus on the development of innovative computational approaches for post-genomic systems biology, statistical methods for high-throughput biological experimentation and the dynamic modelling of cellular systems. This work is highly interdisciplinary and usually involves close collaboration with experimental biologists and clinicians. A recurrently theme is the study of complex cellular networks at ...