Web page: http://www.uva.nl
City: The Netherlands
Nieuwe Achtergracht 166
Projects: SulfoSys, FAIRDOM user meeting, Service to Milano-Bicocca with respect to their ATP-ROS model (Active NOW), Delete, Service to University of Lisbon (Portugal) with respect to their CFTR maturation model (Active NOW), Service to LCSB (Luxembourg) with respect to ROS management in Parkinson’s disease and cancer model (Active NOW), Service to URV Tarragona, Spain with respect to their Safety Assessment of Endocrine Disrupting Chemicals model (Active NOW), Service to Universidade Católica Portugues with respect to their Molecular Insight into Autism Spectrum Disorder (ASD) model (Active NOW), Service to Slovenia with respect to their Protease signaling network in neurodegeneration model (Active NOW), Service to University of Duisburg- Essen (Germany): with respect to their The Yin-Yang of Metabolism; Endometatoxicity (YYME) model (Active NOW), Service to Sheffield University (UK): with respect to Mitochondrial perfect adaptation model (Active NOW), Service to Sanquin (Amsterdam): with respect to Modelling of acute and chronic inflammation (Prospective), Service to Munich (Germany): with respect toCharged peptide to charged membrane binding model (Prospective), Training Hunfeld, Glycon proposal preparation
Executive director of ISBE.NL
Institutions: University of Amsterdam
Disciplines: Not specified
Roles: Not specified
Expertise: Not specified
Tools: Not specified
Professor of Experimental Neuroendocrinology at the Academic Medical Center (AMC) and the Hypothalamic Integration Mechanisms group at the Netherlands Institute for Neuroscience (NIN), Amsterdam, The Netherlands
My major projects focus on understanding how the hypothalamic biological clock controls hormonal rhythms and energy metabolism. For this we mainly use the rat as an animal model. Important techniques include blood sampling from and targeted brain infusions in awake and
Professor of Systems Medicine/Biology at the Academic Medical Center, Amsterdam and University Medical Center Groningen, Groningen, The Netherlands
My major projects focus on understanding the etiology of metabolic syndrome and its comorbidities type2 diabetes and cardiovascular disease. To get grip on the sequence of events in disease progression we make use of longitidunal models and apply multiscal systems biology approaches.
My published work can be found at:
Prof. Dr. Natal van Riel is Professor in Computational Modelling at the Academic Medical Center - University of Amsterdam (AMC - UvA) and Associate Professor in Systems Biology and Metabolic Diseases at the Department of Biomedical Engineering of the Eindhoven University of Technology (TU/e).
My research applies mathematical modelling and computation to study metabolic diseases, in particular Metabolic Syndrome and co-morbidities. Systems biology approaches are developed for
I am an emeritus professor in Biochemistry at the University of Amsterdam (retired 2010).
My research focussed on the human chromatin in its natural environment, i.e. the nucleus of cultured living human cells.
Aspects, such as the dynamic folding of the chromatin fiber inside the nucleus and local chemical modification of histones and DNA at genetic loci, are the physical and chemical basis for epigenetic regulation of gene expression. In my group we worked parallel on human
We are modelling ROS management and mitochondrial dysfunction. Mitochondria produce both energy and reactive oxygen species (ROS), and suffer from ROS. Experimental data from University Milan-Bicocca.
Public web page: Not specified
"Systems Understanding of Microbial Oxygen responses" (SUMO) investigates how Escherichia coli senses oxygen, or the associated changes in oxidation/reduction balance, via the Fnr and ArcA proteins, how these systems interact with other regulatory systems, and how the redox response of an E. coli population is generated from the responses of single cells. There are five sub-projects to determine system properties and behaviour and three sub-projects to employ different and complementary modelling