Sustained glycolytic oscillations in individual isolated yeast cells - IV
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Using optical tweezers to position yeast cells in a microfluidic chamber, we were able to observe sustained oscillations in individual isolated cells. Using a detailed kinetic model for the cellular reactions, we simulated the heterogeneity in the response of the individual cells, assuming small differences in a single internal parameter. By operating at two different flow rates per experiment, we observe four of categories of cell behaviour. The present model (gustavsson4) predicts the steady-state behaviour observed in 25.7% of the cell population.


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  • gustavsson4.dat (uuencoded file - 11.7 KB) Download

Organism: Saccharomyces cerevisiae

Model type: Ordinary differential equations (ODE)

Model format: Not specified

Execution or visualisation environment: JWS Online

Model image: No image specified

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Views: 2993   Downloads: 152

Created: 23rd Jul 2012 at 23:17

Last updated: 23rd Oct 2012 at 13:42

Last used: 20th Apr 2019 at 02:56

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