Basic regulatory principles of Escherichia coli’s electron transport chain for varying oxygen conditions in glucose-limited continuous cultures

Goals:
1. Understanding the regulatory principles of Escherichia coli’s electron transport chain (ETC) for varying oxygen conditions in glucose-limited continuous cultures (especially regulatory loops via the transcription factors FNR and ArcA).
2. Explaining the observed phenomena in the measurement data.
3. Predicting unmeasured variables especially of the gene expression regulatory loops.

Means:
1. Experiments (chemostat experiments within the aerobiosis scale).
2. Kinetic modelling (especially of the ETC).

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Created: 4th Mar 2011 at 16:58

Last updated: 22nd Nov 2011 at 20:12

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