The model describes the electron transport chain (ETC) of Escherichia coli by ordinary differential equations. Also a simplified growth model based on an abstract reducing potential describing the balance of electron donor (glucose) and electron acceptors is coupled to the ETC. The model should reproduce and predict the regulation of the described system for different oxygen availability within the aerobiosis scale (glucose limited continuous culture<=>chemostat). Therefore oxygen is changed slowly over time (linear increase) and the simulated variables can be considered as steady-states for single fixed oxygen concentrations (anaerobic=> microaerobic=> aerobic) in the inflowing gas. Time=20000 corresponds to 100% aerobiosis (end of model validity). Different glucose concentrations Glcin and dilution rates Dil can be simulated by changing the corresponding parameters and the parameter JO2in100 for the maximal oxygen flow.
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Created: 30th May 2011 at 10:09
Last used: 21st Apr 2019 at 19:59