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Batch and chemostat model of L lactis. Scope of the model is to provide a mechanistic explanation of the switch between mixed acid and homolactic fermentation.
Creator: domenico bellomo
Submitter: domenico bellomo
Model type: Partial differential equations (PDE)
Model format: Matlab package
Environment: Matlab
The principles of Stealthy Engineering (Adamczyk et al.: Biotechnology Journal 2012; 7(7):877-83) are illustrated in this model by emulating a cross engineering intervention between L. lactis and S. cerevisiae.
The case study consists of replacing the native glucose uptake system of L. lactis with that native to the yeast S. cerevisiae. A modified version of Hoefnagel et al.’s model of L. lacrtis’ central metabolism was used as starting point. The total functional replacement of the PTS with the ...
Creators: Malgorzata Adamczyk, Hans V. Westerhoff, Ettore Murabito
Submitter: Ettore Murabito
Model type: Ordinary differential equations (ODE)
Model format: Copasi
Environment: Copasi