Combinatorial mutant, perturbation and time series predictions

Simulation of double mutants and perturbations and time series samples using for Sample 1 only OE mutants of which we update the enzyme concentrations. For each second mutant the enzyme concentrations in case of OE and KO mutants in updated and the metabolite concentrations of the second sample are loaded in the model.
Using this approach the model approximately predicts combinatorial effects of OE mutations with other mutations, perturbations and time series concentrations.

FAIRDOMHub ID: https://seek.sysmo-db.org/assays/523

Modelling Analysis

Niels Zondervan

Projects: MycoSynVac - Engineering Mycoplasma pneumoniae as a broad-spectrum anima...

Investigation: hidden item

Study: Core model combinatorial predictions

Biological problem addressed: Modelling Analysis

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Created: 1st May 2017 at 12:21

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