I am interested in the coupling of global regulation and metabolism in E. coli. To analyze this I construct and analyze defined mutant strains. These strains are characterized in bioreactor experiments of different types (batch, conti, pulse ...) and measurements on the level of metabolites, mRNA, and protein are applied. For all projects there are cooperation partners that use the data in modeling approaches either from the MPI Magdeburg or from the SUMO consortium.
Post-doctoral research associate working in Sheffield in the SUMO consortium.
Tools: fed-batch cultivation, In silico Metabolic Network Analysis, Dynamic modelling, including:- Dynamic modelling- Parameter estimation- Optimal experimental design- Dynamic optimization, Computational Systems Biology, evaluation of process dynamics, continuous cultivation, stimulus response experiments, Fermentation
Professor for Biochemcial Engineering, University Stuttgart
Dr. Bettina Schiel-Bengelsdorf
Department of Microbiology and Biotechnology
University of Ulm
89069 Ulm, Germany