Projects: Not specified
Institutions: Not specified
Projects: KOSMOBAC
Institutions: Max-Planck-Institute of Biochemistry Martinsried
Expertise: translational control of gene expression, translatome, folding pathways, Molecular Biology, Biochemistry
Tools: Molecular biology techniques (RNA/DNA), Fluorescence and confocal microscopy FRAP/FLIP, quantitative western blot analysis, fluorescence spectroscopy, rtPCR, Spectroscopy and structural analysis, Biochemistry and protein analysis
The focus of our research is the protein biogenesis and how stress-related factors modulate it. Protein biogenesis in general comprises various processes, i.e., translation, protein folding, each of which responds differently to external stress stimuli. Using systems biology approaches we seek to understand the interplay between these processes in fine-tuning the protein pattern and proteins’ abundance under osmotic stress conditions.
Projects: KOSMOBAC
Institutions: University of Aberdeen
I am postdoc in the group of Prof Ian Booth in Aberdeen working on the biochemical and biophysical characterisation of bacterial channels.
Projects: BaCell-SysMO
Institutions: University of Newcastle
Expertise: Bacterial Cell Biology, fluorescence protein fusions, localisation studies, Cell physiology, membrane biology, metal ion homeostasis, Molecular Biology, Microbiology
Tools: Time-lapse fluorescence microscopy, Fluorecence based reporter gene analyses/single cell analyses, fluorescence spectroscopy, Fluorescence and confocal microscopy
Projects: KOSMOBAC
Institutions: University of Groningen
Kosmobac, WP3, looking at diffusion of macromolecules in vivo (in E.coli cells) and cell responses to osmotic shock using confocal (fluorescence) microscopy especially pulsed - FRAP
Projects: KOSMOBAC
Institutions: Max-Planck-Institute of Biochemistry Martinsried
I am a PhD student working the group of Zoya Ignatova. Cellular and extracellular changes like crowding and osmotic stress conditions play a major role in protein aggregation. A change in the cytoplasmic composition is the result of an interplay between high osmotic pressures outside the cell volume and the cellular response to it in terms of uptake of K+ and secondary organic osmolytes. My research focuses on elucidating the role of natural osmolytes (known also as chemical chaperones or compatible
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