Studies
What is a Study?Filters
Provided with genomic data over different pH values we have the opportunity to study the similarity of gene expression profiles and cluster groups of very simlar gene expression profiles. Via PCA we can furthermore study dynamic similarity and compe genes that are possible co-regulators or anti-regulators in the clostridial metabolism.
Submitter: Sebastian Curth
Investigation: The effect of pH upon the metabolic shift in Cl...
Assays: Identification of dynamically similar transcript profiles
The aim of the study is to assess the global function of RNase Y in RNA processing and degradation in Bacillus subtilis. To this end we constructed a strain allowing controlled depletion of RNase Y and used microarrays to analyze the transcriptome in response to the expression level of RNase Y.
Submitter: Praveen kumar Sappa
Investigation: Identification of targets of the essential RNas...
Assays: Transcritome data_Identification of targets of the essential RNase Y of ...
Submitter: Daniel Hönicke
Investigation: Altering the expression pattern in Clostridium ...
Assays: Transcriptional analyses of a thioredoxin (trxB, encoded by CAC1548) kno...
Submitter: Nikolay Zenkin
Investigation: Wetlab approach to transcription fidelity
Assays: Kinetics of misincorporation and proofreading by bacterial RNA polymerase
test test
Submitter: Holger Janssen
Investigation: Systems Biology of Clostridium acetobutylicum -...
Assays: test
How do the fluxes of rubidium (potassium) change during potassium starvation.
Submitter: Falko Krause
Investigation: K+ Starvation in Saccharomyces cerevisiae
Assays: Ammonium fluxes, Potassium fluxes, Proton fluxes
How does the flux of potassium, hydrogen change during potassium uptake? Which ions are involved in maintaining the required charge balance?
Submitter: Falko Krause
Investigation: Potassium uptake in Saccharomyces cerevisiae
Assays: Additional fluxes, Potassium fluxes, Proton fluxes
The output of the initial model of redox metabolism will be compared to experimental flux and metabolite data. Deviations between model and experiment will be prioritized together with WP2. We will apply Metabolic Control Analysis (Fell 1992 PMID: 1530563) to diagnose which enzymes control the deviating metabolite concentrations and/or rates. When the agreement between model and experiment is sufficient we will first link it to the existing model of trypanosome glycolysis and repeat the same ...
Submitter: Jurgen Haanstra
Investigation: Dynamic modelling of redox metabolism and gene ...
Assays: No Assays