Physical chemist with expertise in experimental kinetics, molecular biology, and mathematical modeling.
MOSES (Micro Organism Systems biology: Energy and Saccharomyces cerevisiae) develops a new Systems Biology approach, which is called 'domino systems biology'. It uses this to unravel the role of cellular free energy ('ATP') in the control and regulation of cell function. MOSES operates though continuous iterations between partner groups through a new systems-biology driven data-management workflow. MOSES also tries to serve as a substrate for three or more other SYSMO programs.
The model describes the Entner-Doudoroff pathway in Sulfolobus solfataricus under temperature variation. The package contains source code written in FORTRAN as well as binaries for Mac OSX, Linux, and Windows. If compiling from source code, a FORTRAN compiler is required.
On-line versions of the model are also available at:
Creator: Peter Ruoff
Contributor: Peter Ruoff
Model type: Ordinary differential equations (ODE)
Model format: Not specified
Organism: Sulfolobus solfataricus
Environment: Not specified
Date Published: 12th Jul 2017
Journal: PLoS One
PubMed ID: 28692669
Citation: PLoS One. 2017 Jul 10;12(7):e0180331. doi: 10.1371/journal.pone.0180331. eCollection 2017.
Date Published: 23rd Dec 2009
Journal: PLoS ONE
PubMed ID: 20502716