MESI-STRAT: Systems Medicine of Metabolic-Signaling Networks -A New Concept for Breast Cancer Patient Stratification.
Breast cancer is a complex disease with high prevalence in the European Union and world-wide. 75%-80 of the patients have estrogen receptor-positive (ER)-positive tumors and are treated with endocrine therapies. Endocrine therapies, which block ER-driven tumor growth, show high efficacy. Yet, a significant proportion of the patients will eventually relapse with metastatic breast
Programme: This Project is not associated with a Programme
Comment: The cells were sent to CHAB from Opitz lab and STR profiled to confirm their identity. Their mutational pattern was analysed by panel DNA sequencing as described in file "MESI-STRATcells.docx".