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OptKnock algorithm was used as part of a study in RobOKoD: microbial strain design for (over)production of target compounds. (http://fairdomhub.org/publications/236). It was used to generate a strain of e.coli for producing butanol, that was then compared to an experimental strain.
Contributor: Natalie Stanford
Biological problem addressed: Metabolic Redesign
Investigation: Designing a new way to predict engineering stra...